Fig. 3

a–g Concentrations of pro- (a–g) and anti- (h–j) inflammatory cytokines released from donor #7 sample groups to the medium during 14-day cultures. Concentrations of pro-inflammatory cytokines were higher in the synovial monocultures and CBS cocultures, suggesting that the synovium tissue was the primary source of these cytokines. C, cartilage monocultures; CB, intact osteochondral plugs; CBS, osteochondral plugs cocultured with synovium; S, synovium explant monocultures