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Table 1 Characteristics of patients and controls and markers of r-axSpA disease activity before and after anti-TNF treatment

From: Serum granulocyte-macrophage colony-stimulating factor (GM-CSF) is increased in patients with active radiographic axial spondyloarthritis and persists despite anti-TNF treatment

 

Patients

Controls

p

N

12

16

 

Males (N)

7

11

0.7

Median age, years (range)

37 (22–52)

37 (22–55)

0.65

Median disease duration since diagnosis, years (range)

1 (0.5–25)

NA

 

Median disease duration since symptom onset, years (range)

6.5 (0.5–29)

NA

 

HLA B27 positive, N (%)

8 (66.7)

ND

 
 

Baseline

Follow-up

  

Mean CRP (SD), mg/dL

0.58 (0.5)

0.16 (0.2)

ND

 

Mean BASDAI (SD)

6.3 (2)

4.1 (1.7)

NA

 

Mean ASDAS (SD)

3.2 (0.7)

2.2 (0.6)

NA

 
  1. ASDAS, Ankylosing Spondylitis Disease Activity Score; BASDAI, Bath Ankylosing Spondylitis Disease Activity Index; CRP, C-reactive protein; r-axSpA, radiographic axial spondyloarthritis; NA, not applicable, ND, not done; TNF, tumor necrosis factor