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Table 2 Mean change in Hb levels over time by treatment arm (TARGET, MOBILITY, and MONARCH)

From: Association between low hemoglobin, clinical measures, and patient-reported outcomes in patients with rheumatoid arthritis: results from post hoc analyses of three phase III trials of sarilumab

Hb (g/L)

Baseline

Mean change from baseline to 24 weeks

Mean change from baseline to 52 weeks

TARGET

 Placebo + DMARD

126.6

− 0.3

–

 Sarilumab 150 mg q2w + DMARD

128.1

+ 8.0

–

 Sarilumab 200 mg q2w + DMARD

125.7

+ 9.0

–

MOBILITY

 Placebo + MTX

127.0

− 0.3

− 0.6

 Sarilumab 150 mg + MTX

125.6

+ 7.9

+ 9.1

 Sarilumab 200 mg + MTX

126.6

+ 8.2

+ 10.0

MONARCH

 Adalimumab 40 mg q2w

129.5

+ 1.1

–

 Sarilumab 200 mg q2w

130.1

+ 6.0

–

  1. Mean changes in Hb levels were reported at baseline, week 24, and week 52 (MOBILITY-B only)
  2. DMARD disease-modifying antirheumatic drugs, Hb hemoglobin, q2w every 2 weeks, SD standard deviation