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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Circ0007042 alleviates intervertebral disc degeneration by adsorbing miR-369 to upregulate BMP2 and activate the PI3K/AKt pathway

Fig. 6

circ_7042 regulates the expression of apoptosis- and collagen metabolism-related proteins in NP cells through the miR-369-3p/BMP2 axis. A Western blotting was used to detect cleaved caspase-3, total caspase-3, Bax, and Bcl-2 protein expression levels. B–D The optical density of the protein bands in A was statistically quantified by Western blot detection. E The expression levels of BMP2, collagen II, aggrecan, MMP-13, and MMP-3 proteins were detected by Western blotting. F–J Western blotting results: statistical quantification results of optical density values of protein bands in E. *P<0.05, **P<0.01, the two groups were compared between the wires

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