Fig. 9

circ_7042 inhibits LSI-induced NP cell apoptosis and collagen degradation through the BMP2/PI3K/Akt pathway. A Western blotting was used to detect PI3K/Akt protein and phosphorylation levels and Bcl-2, Bax, total caspase-3, and cleaved caspase-3 protein expression levels. B–F The optical density of the immunoblotting protein bands was statistically quantified. G The expression levels of CDH2, BMP2, collagen II, aggrecan, MMP-13, and MMP-3 proteins were detected by Western blotting. H–M Statistical quantification results of optical density values of Western blotting protein bands. *P<0.05, **P<0.01, the two groups were compared between the wires