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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Identification of HBEGF+ fibroblasts in the remission of rheumatoid arthritis by integrating single-cell RNA sequencing datasets and bulk RNA sequencing datasets

Fig. 3

Bioinformation of HBEGF+ fibroblasts. a HBEGF+ fibroblasts of RA synovium are displayed at UMAP. b Differential gene expression of HBEGF+ fibroblasts and HBEGF− fibroblasts are shown in a volcano plot. c Heatmap shows top 10 expressed gene markers of each cluster. d HBEGF expression in synovial fibroblasts (n = 25) and macrophages (n = 12) by bulk RNA sequencing (P = 0.7911) are plotted as log2 count + 1. e Differential expression genes between high HBEGF group and low HBEGF group are highlighted on the HBEGF+ fibroblast versus HBEGF− fibroblast plot from b. f, g GO enrichment analysis of HBEGF+ fibroblasts (f) and HBEGF− fibroblasts (g)

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Arthritis Research & Therapy

ISSN: 1478-6362

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