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Table 2 Performance of radiographically detectable dvOPs with regard to diagnostic testing of HOA. HOA was determined by either radiographic (Kellgren/Lawrence) or histological (Mankin) scoring systems. PPV, positive predictive value; NPV, negative predictive value

From: Dorso-ventral osteophytes of interphalangeal joints correlate with cartilage damage and synovial inflammation in hand osteoarthritis: a histological/radiographical study

n

OA according to Kellgren/Lawrence

OA according to Mankin

dvOPs in DIP

 Sensitivity

81.82% (59.72 to 94.81%)

69.23% (48.21 to 85.67%)

 Specificity

100% (78.20 to 100%)

100% (71.51 to 100.00%)

 PPV

100%

100%

 NPV

78.95% (60.71 to 90.10%)

57.89% (43.58 to 70.99%)

dvOPs in PIP

 Sensitivity

54.55 % (23.38 to 83.25%)

25.00% (9.77 to 46.71%)

 Specificity

100% (87.66 to 100%)

100% (78.20 to 100%)

 PPV

100%

100%

 NPV

84.85% (74.56 to 91.45%)

45.45% (39.81 to 51.22%)