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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Single-cell analysis reveals heterogeneity of juvenile idiopathic arthritis fibroblast-like synoviocytes with implications for disease subtype

Fig. 1

Expression of universal fibroblast markers. Markers consist of FBLN1, FBLN2, PDGFRA, COL1A2, COL5A1, COL1A1, LOXL1, LUM, and CD34. Determined that 92% of oligoarticular JIA FLS express fibroblast markers, 90% of ETB JIA FLS express fibroblast markers, and 94% of poly JIA FLS express fibroblast markers (A), establishing that our initial total cell input has fibroblast origins. Heatmaps provide visualizations of the expression of the individual fibroblast markers and their expression pattern in individual cell clusters (B). A combination of upregulated and downregulated expression of these markers in individual clusters defines cells as fibroblast

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Arthritis Research & Therapy

ISSN: 1478-6362

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