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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Therapeutic effects of adipose-derived mesenchymal stem/stromal cells with enhanced migration ability and hepatocyte growth factor secretion by low-molecular-weight heparin treatment in bleomycin-induced mouse models of systemic sclerosis

Fig. 2

In vivo migration of mASCs cultured in different LMWH concentrations was assessed by IVIS system. A Representative accumulation image of ICG-labelled mASCs in each organ after 24 h of mASC administration. The images are displayed with a minimum-maximum scale of 4 × 106 to 2 × 107 photons/s/cm2/steradian. B The signal intensities in the skin were significantly increased in mASCs with 10 μg/mL LMWH, but there was no significant difference in mASCs with 100 μg/mL LMWH. For the signal intensities in the spleen, thymus, heart, lungs, liver, and kidneys, there was no difference. Data are shown as mean ± SEM. **P < 0.01 vs. mASCs without LMWH. Sk, skin; T, thymus; Sp, spleen; H, heart; Lu, lungs; Li, liver; K, kidneys

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Arthritis Research & Therapy

ISSN: 1478-6362

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