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Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: Cationic amino acid transporter-1 (CAT-1) promotes fibroblast-like synoviocyte proliferation and cytokine secretion by taking up L-arginine in rheumatoid arthritis

Fig. 7

Inhibition of L-arginine uptake suppresses CIA mouse induction. a Swellings of paws and joints were more apparent in control mice (n = 6) compared with L-arginine deprivation (n = 6) and D-arginine addition (n = 6) mice. b Average arthritic index of control, L-arginine deprivation, and D-arginine addition mice were evaluated. c H&E staining analysis of inflammatory cell infiltration in the joint from each group. d Inguinal lymph nodes from each group were collected and photographed. The data are expressed as the mean ± SD of three independent experiments. *P < 0.05

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Arthritis Research & Therapy

ISSN: 1478-6362

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