EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis

Table 1 Clinical characteristics of patients with rheumatoid arthritis

Patient number	1	2	3	4
Age	47	54	64	41
Sex	M	F	F	F
Body mass index	25.0	25.5	22.0	21.7
Disease duration	72 months	176 months	140 months	281 months
RF	175.9	199.6	108.3	72.3
Anti-CCP titer	340	100	80	7.6
DAS28-CRP	2.48	2.3	2.45	3.32
ESR	25	3	4	19
CRP	0.20	0.29	0.38	0.47
Medication	MTX + tocilizumab + prednisolone 5mg	MTX	MTX	MTX + tacrolimus +prednisolone 5mg
Comorbid disease	Hyperlipidemia	Osteoporosis	Diabetes mellitus, osteoporosis, hyperlipidemia	Osteoporosis

M male, F female, mo month, RF rheumatoid factor (normal < 14 IU/ml), anti-CCP anti-cyclic citrullinated peptide antibody (normal < 5 units/ml), DAS28 disease activity score 28, CRP c-reactive protein (mg/dL), ESR erythrocyte sedimentation rate (mm/h), MTX methotrexate

ISSN: 1478-6362