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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Rheumatoid arthritis sera antibodies to citrullinated collagen type II bind to joint cartilage

Fig. 4

IHC staining results of promiscuous and private groups. A Mean arthritis score (0–60) of the CIA experiment with DBA1/J. B Hematoxylin-eosin staining of naïve mouse hind paw and arthritic DBA1/J hind paw (arthritis score > 12). C Representative IHC staining results from promiscuous, private and HC sera. D MOD is a parameter to measure the in vitro reactivity of sera to naïve and arthritic joint tissue. 40X, 400X: the magnification of pictures. MOD: mean of integrated optical density. pro-RA: promiscuous RA sera; pro-OA: promiscuous OA sera; pri-RA: private RA sera; pri-OA: private OA sera; HC: healthy individuals sera

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