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Table 2 The prevalence and the extent of skin sclerosis, lung, and heart involvement at the first DNSS visit were indicated for HSCT and control groups A and B

From: Autologous hematopoietic stem cell transplantation improves long-term survival—data from a national registry

Baseline DNSS visit

 

HSCT

all dc-SSc  controls A

p

dc-SSc+ Scl70+ male controls B

p

Patient number (N)

80

1513

---

240

 

Patient number valid n (%)

78 (97.5)

1241 (82.0)

---

218 (90.3)

 

mRSS (mean ± SD)

17.7 ± 11.7

15.6 ± 9.9

0.156

17.2 ± 9.7

0.860

mRSS < 10 (N (%))

25 (32.1)

423 (34.1)

0.805

59 (27.1)

0.464

mRSS > 10

53 (68.0)

818 (65.9)

 

159 (72.9)

 

mRSS > 15

42 (53.8)

557 (44.9)

0.128

115 (52.8)

0.895

mRSS > 20

32 (41.0)

350 (28.2)

0.020

70 (32.1)

0.167

Lung involvement

PAH only

0

58 (  3.8)

0.186

9 (3.8)

0.288

ILD only

42 (52.5)

658 (43.5)

 

113 (47.1)

 

PAH + ILD

11 (13.8)

171 (11.3)

 

28 (11.7)

 

none

26 (32.5)

522 (34.5)

 

87 (36.3)

 

DLCO SB valid data (N (%))

60 (75.0)

829 (54.8)

0.001

163 (67.9)

0.147

DLCO SB (%, mean ± SD)

53.9 ± 17.9

63.2 ± 21.9

0.006

59.1 ± 21.3

0.124

DLCO SB <75% (N (%))

53 (88.3)

633 (76.4)

 

129 (79.1)

 

Heart involvement (N (%))

19 (23.8)

243 (16.1)

0.131

52 (21.7)

0.756