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Table 3 Clusters changes in cortical thickness in non-NPSLE group compared with HCs (SBM analyses)

From: Abnormal cortical thickness and structural covariance networks in systemic lupus erythematosus patients without major neuropsychiatric manifestations

Contrast

 

Cortical regions

Size (mm2)

xyz-peak (MNI)

P-value

non-NPSLE<HCs

Left

S_circular_insula_sup

2941.56

−31.0/20.3/12.5

0.0001

S_front_middle

2152.76

−27.6/45.3/14.1

0.0001

S_cingul-Marginalis

1469.93

−18.7/−38.9/44.8

0.0001

S_front_inf

1101.96

−40.3/26.1/16.8

0.0001

S_temporal_sup

878.23

−55.3/−32.0/−11.2

0.0001

G_oc-temp_lat-fusifor

853.72

−31.3/−68.7/−14.9

0.0001

S_temporal_sup

794.76

−37.9/−55.4/18.9

0.0001

S_parieto_occipital

737.21

−17.6/−75.1/23.7

0.0001

S_front_sup

545.85

−21.7/17.6/53.8

0.0001

G_rectus

526.56

−4.5/46.8/−19.8

0.0001

G_front_sup

451.51

−7.7/29.9/45.9

0.0001

S_orbital-H_Shaped

441.84

−19.5/28.3/−15.4

0.0001

S_intrapariet_and_P_trans

436.74

−17.3/−70.7/40.5

0.0001

G_pariet_inf-Supramar

348.93

−50.4/−46.0/44.8

0.0003

G&S_paracentral

311.81

−6.1/−42.7/68.4

0.0006

G_occipital_middle

306.69

−41.5/−83.2/4.2

0.0007

S_oc-temp_med_and_Lingual

188.53

−30.4/−41.9/−8.6

0.0123

S_intrapariet_and_P_trans

144.67

−27.0/−56.3/39.9

0.0397

Right

G_front_middle

9634.23

26.1/42.8/31.6

0.0001

G_oc-temp_lat-fusifor

2804.26

33.0/−57.6/−15.0

0.0001

G_precuneus

1967.74

6.2/−54.8/16.6

0.0001

G_pariet_inf-Angular

845.03

34.2/−61.6/44.7

0.0001

S_orbital_med-olfact

630.71

10.2/35.3/−19.9

0.0001

G&S_cingul-Mid-Ant

552.84

13.0/19.3/37.2

0.0001

S_oc_sup_and_transversal

479.05

27.8/−65.3/26.3

0.0001

S_parieto_occipital

392.62

18.5/−64.3/6.0

0.0001

S_occipital_ant

279.71

43.4/−64.3/31.5

0.0005

G_temp_sup-Plan_polar

245.21

53.6/0.1/−7.9

0.0025

S_precentral-sup-part

240.50

22.6/−8.1/49.6

0.0031

G_temp_sup-Plan_tempo

215.61

61.9/−22.8/5.8

0.0067

G_precuneus

203.79

6.8/−50.7/60.3

0.0088

S_oc_middle_and_Lunatus

180.95

42.2/−78.2/6.2

0.0160

S_temporal_sup

167.49

49.0/−30.0/1.2

0.0221

Pole_occipital

139.25

13.2/−101.2/8.2

0.0439

non-NPSLE>HCs

-

-

-

-

-

  1. Based on Destrieux atlas with 148 brain regions. HCs, healthy controls; MNI, Montreal Neurological Institute