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Table 4 Results from the Principal Component Analyses including MTX initiators

From: Four emerging immune cellular blood phenotypes associated with disease duration and activity established in Psoriatic Arthritis

 

Contribution of individual cell type to the component (%)

Coefficients with correlation between cells type and components

Component

Component

1

2

3

4

1

2

3

4

Tc cells

4.05

13.03

3.16

47.33

0.33

0.51

-0.22

0.69

Th1 cells

0.03

32.06

5.12

0.01

-0.03

0.80

0.28

0.01

Th17 cells

16.44

13.53

0.57

8.33

-0.66

0.52

0.09

-0.29

nTregs

4.04

10.89

32.60

0.31

-0.32

-0.46

0.71

0.06

amTregs

29.69

0.93

0.41

5.37

-0.88

-0.14

0.08

0.23

umTregs

21.94

1.93

2.11

20.86

-0.76

0.20

0.18

0.46

Dendritic cells

18.77

0.04

9.71

7.91

-0.70

0.03

-0.39

-0.28

NK cells

0.05

26.00

0.71

9.17

-0.04

0.72

0.01

-0.30

Monocytes

5.00

1.60

46.33

0.71

-0.36

-0.18

-0.18

0.08

  1. Important contribution to the component was defined as contribution above the average ~11.1%. Correlation coefficients >0.50 were considered strong. Bold text represents values of important contribution and strong correlation coefficients, respectively
  2. MTX methotrexate, Tc CD8+ cytotoxic T cells, Th1 T helper cell type 1, Th17 T helper cell type 17, nTregs naïve T regulatory cells, amTregs activated memory T regulatory cells, umTregs unactivated memory T regulatory cells, NK cells natural killer cells