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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: Early removal of the infrapatellar fat pad/synovium complex beneficially alters the pathogenesis of moderate stage idiopathic knee osteoarthritis in male Dunkin Hartley guinea pigs

Fig. 6

MCP-1 and NF-kB p65 immunohistochemistry of medial tibia plateau (MTP) articular cartilage. 40× objective representative images of MTP articular cartilage immunostained for MCP-1 from IFP/SC (A) and FCT-containing knees (B) of the same animal. (C) Figure representing quantitative analysis of MCP-1-stained tissue subtracted from IgG control tissue for all samples. IHC for NF-kB p65 was also significantly decreased in FCT knees compared (E) to IFP/SC knees (D). (G) Figure representing quantitative analysis of p65 stained tissue subtracted from IgG control tissue for all samples. Data was normally distributed and compared using parametric ratio paired t test†. *** P < 0.0005 and * P< 0.05

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