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Table 3 Maternal outcomes in ART. Pa, comparisons among three groups. Pb, comparison between ART and planned pregnancy. Pc, comparison between ART and unplanned pregnancy. Pd, comparison between planned and unplanned pregnancy

From: Pregnancy outcomes in patients receiving assisted reproductive therapy with systemic lupus erythematosus: a multi-center retrospective study

 

ART (n = 66)

Planned (n = 214)

Unplanned (n = 66)

Pa

Pb

Pc

Pd

Mode of delivery

 Natural labor, n (%)

18 (27.3)

72 (33.6)

11 (16.7)

0.028

0.368

0.207

0.009

 Cesarean section, n (%)

42 (63.6)

126 (58.9)

12 (18.2)

 < 0.001

0.566

 < 0.001

 < 0.001

Outcomes

 GDM, n (%)

15 (22.7)

16 (7.5)

1 (1.5)

 < 0.001

0.001

 < 0.001

0.084

 Disease flares, n (%)

10 (15.2)

23 (10.7)

52 (78.8)a

 < 0.001

0.382

 < 0.001

 < 0.001

 PPROM, n (%)

9 (13.6)

54 (25.2)

2 (3.0)

 < 0.001

0.063

0.055

 < 0.001

 Preeclampsia, n (%)

5 (7.6)

13 (6.1)

0 (0)

0.056

   

 Gestational hypertension, n (%)

3 (4.5)

7 (3.3)

2 (3.0)

0.913

   

 Eclampsia, n (%)

1 (1.5)

14 (6.5)

4 (6.1)

0.313

   

 Premature delivery, n (%)

21 (31.8)

48 (22.4)

14 (21.2)

0.259

   

 Fetal loss, n (%)

6 (9.1)

16 (7.5)

43 (65.2)

 < 0.001

0.794

 < 0.001

 < 0.001

 Twins, pairs, n (%)

5 (7.6)

3 (1.4)

0 (0)

0.019

0.020

0.058

1.000

  1. Abbreviation: ART Assisted reproductive therapy, GDM Gestational diabetes mellitus, PIH Pregnancy-induced hypertension, PPROM Preterm premature rupture of membranes, SLE Systemic lupus erythematosus
  2. aIncluding 19 pregnancies with new onset of SLE after pregnancy