Table 4 Manifestation of disease flares. Pa, comparisons among three groups. Pb, comparison between ART and planned pregnancy. Pc, comparison between ART and unplanned pregnancy. Pd, comparison between planned and unplanned pregnancy
ART (n = 10) | Planned (n = 23) | Unplanned (n = 52) | Pa | Pb | Pc | Pd | |
|---|---|---|---|---|---|---|---|
Disease activity | |||||||
Mild, n (%) | 4 (40.0) | 23 (100) | 13 (25.0) | < 0.001 | 0.004 | 0.440 | < 0.001 |
Moderate, n (%) | 5 (50.0) | 0 (0) | 11 (21.2) | 0.001 | 0.001 | 0.107 | 0.015 |
Severe, n (%) | 1 (10.0) | 0 (0) | 28 (53.8) | < 0.001 | 0.303 | 0.015 | < 0.001 |
Time of disease flares | |||||||
First trimester, n (%) | 1 (10.0) | 6 (26.1) | 28 (53.8) | 0.008 | 0.397 | 0.015 | 0.043 |
Second trimester, n (%) | 3 (30.0) | 11 (47.8) | 20 (38.5) | 0.580 | |||
Third trimester, n (%) | 6 (60.0) | 6 (26.1) | 1 (1.9) | < 0.001 | 0.114 | < 0.001 | 0.003 |
Puerperium, n (%) | 0 (0) | 0 (0) | 3 (5.8) | 0.691 | |||
Manifestations | |||||||
Nephritis, n (%) | 8 (80.0) | 18 (78.3) | 28 (53.8) | 0.050 | |||
Proteinuria, n (%) | 8 (80.0) | 17 (73.9) | 28 (53.8) | 0.125 | |||
Hematuria, n (%) | 2 (20.0) | 1 (4.3) | 3 (5.8) | 0.716 | |||
Pyuria, n (%) | 1 (10.0) | 0 (0) | 0 (0) | 0.182 | |||
Thrombocytopenia, n (%) | 5 (50.0) | 4 (17.4) | 19 (36.5) | 0.329 | |||
Leukopenia, n (%) | 1 (10.0) | 2 (8.7) | 4 (7.7) | 0.182 | |||
Rash, n (%) | 1 (10.0) | 0 (0) | 11 (21.2) | 0.046 | |||
Hemolytic anemia, n (%) | 0 (0) | 2 (8.7) | 2 (3.8) | 0.716 | |||
NP-SLE, n (%) | 0 (0) | 1 (4.3) | 3 (5.8) | 1.000 | |||
Arthritis, n (%) | 0 (0) | 2 (8.7) | 6 (11.5) | 0.675 | |||