Skip to main content
Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Interferon and interferon-induced cytokines as markers of impending clinical progression in ANA+ individuals without a systemic autoimmune rheumatic disease diagnosis

Fig. 1

Cytokine levels in the ANA+ participant subsets. Scatterplots showing the results for the IFN5 score and the cytokines, IFN-α measured by high-sensitivity ELISA, IFN-α measured by Simoa, CXCL-10, Galectin-9, and IFN-γ (all shown using logarithmic scales). From left to right are shown results for healthy controls (ANAHC), asymptomatic ANA+ individuals (ANA+NS), undifferentiated connective tissue disease (UCTD) patients, and systemic autoimmune rheumatic disease (SARD) patients. Results to the right of the dashed line are those for the individual SARD conditions, SLE, SS, and SSc. Each circle represents a single subject, with the bars indicating the median for the subjects and error bars denoting the interquartile range. Significant differences between ANAHC and the ANA+ groups are indicated with asterisks, *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001, and those between SARD and the other ANA+ subsets indicated with cross hatches, using the same scale

Back to article page