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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Equine osteoarthritis modifies fatty acid signatures in synovial fluid and its extracellular vesicles

Fig. 2

Discriminant analyses depicting the classification of fatty acid (FA) data in equine synovial fluid (SF) (panel A) and its ultracentrifuged extracellular vesicle-enriched pellet (EV) (panel B), and combined data (panel C) from control, contralateral (CL), and osteoarthritic (OA) fetlock joints based on discriminant functions 1 (on x-axis) and 2 (on y-axis). For each sample group, n = 8. In panel A, 16:1n-7, 20:0, 16:0i, 18:3n-3, and DMA 16:0 contributed to function 1, and 18:2n-6, 20:1n-9, 18:0, 20:2n-6, and 22:5n-3 contributed to function 2 with the highest separation power. In panel B, 22:5n-3, 18:3n-6, 20:2n-6, 24:0, and 18:0 contributed to function 1, and DMA 18:0, 17:0i, 20:3n-6, 18:3n-3, 20:0, and 16:0 to function 2, making them the most discriminative FAs between the diagnosis groups. In panel C, 22:0 (function 1), 16:0 (function 2), 18:2n-6, 17:0ai, 14:0, 17:0i, and 16:1n-7 (the last 5 in function 3) had the highest separation power

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