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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: TGF-β is elevated in hyperuricemic individuals and mediates urate-induced hyperinflammatory phenotype in human mononuclear cells

Fig. 1

TGF-β mRNA is upregulated in gout patients and correlates to serum urate levels in the discovery cohort. PBMCs from patients with gout and matched healthy controls (HC) were isolated and adhered to a flat-bottom plate, mRNA was isolated and compared to the mean dCT of healthy controls by Mann-Whitney U tests *p < 0.05 (A, B). Serum urate levels were correlated to relative mRNA expression levels and analysed by Spearman’s correlation (C, D)

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Arthritis Research & Therapy

ISSN: 1478-6362

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