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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: TGF-β is elevated in hyperuricemic individuals and mediates urate-induced hyperinflammatory phenotype in human mononuclear cells

Fig. 2

mRNA expression of TGF-β and downstream targets in PBMCs from individuals with hyperuricemia or gout. PBMCs from individuals with normoruricemia (n = 110), hyperuricemia (n = 22) and gout (n = 72) of which 15 flaring (marked in red) were isolated and transcriptomics were analysed. Relative mRNA expression of TGFB1 (A), MMP9 (B), ITGAV (C) and SMAD7 (D) are shown. Lines represent means with SD. Means were compared by Welch ANOVA with Tamhane’s T2 multiple comparisons test. **p < 0.01

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Arthritis Research & Therapy

ISSN: 1478-6362

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