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Table 2 Logistic regression analysis for CHIP (N = 117)

From: Interplay between chronic inflammation and clonal haematopoiesis of indeterminate potential in Behçet’s disease

Variables

Univariate analysis

Multivariate analysis

OR

95% CI

*p value

OR

95% CI

*p value

Age at blood sampling (years)

1.090

1.030–1.153

0.003

1.099

1.020–1.184

0.013

Disease duration (years)

0.964

0.856–1.084

0.538

   

Sex (male)

0.536

0.164–1.747

0.301

   

Body mass index (kg/m2)

0.934

0.765–1.141

0.504

   

Smoking history

0.914

0.253–3.296

0.890

   

Intestinal BD

4.000

0.496–32.266

0.193

   

Previous medication

 5-ASA

4.640

0.577–37.309

0.149

   

 Corticosteroid

0.398

0.124–1.278

0.122

   

 Immunomodulator

1.018

0.320–3.239

0.976

   

 Anti-TNF

0.745

0.153–3.633

0.716

   

Current medication

 Immunomodulator

0.643

0.131–3.162

0.587

   

 Anti-TNF

1.000

(NS)

    

Laboratory findings at diagnosis

 WBC count (/µL)

1.000

1.000–1.000

0.344

   

 Neutrophil count (/µL)

1.000

1.000–1.000

0.503

   

 Lymphocyte count (/µL)

1.000

1.000–1.000

0.553

   

 Haemoglobin (g/dL)

0.808

0.579–1.128

0.210

   

 Platelet count (/µL)

1.000

1.000–1.000

0.012

1.000

1.000–1.000

0.058

 NLR ratio

1.005

0.891–1.133

0.938

   

 PLR ratio

1.000

1.000–1.000

0.817

   

 ESR (mm/h)

1.027

1.009–1.046

0.004

1.007

0.982–1.033

0.582

 CRP (mg/L)

1.013

0.999–1.028

0.068

   

 Albumin (g/dL)

0.228

0.058–0.887

0.033

0.699

0.075–6.478

0.752

  1. Variables are expressed as mean ± SD or n (%)
  2. CHIP Clonal haematopoiesis of indeterminate potential, OR Odds ratio, CI Confidence interval
  3. *p value for comparing the CHIP( +) and CHIP( −) groups