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Table 4 Subgroup analysis for the association between SII and arthritis

From: The association between systemic immune-inflammation index and rheumatoid arthritis: evidence from NHANES 1999–2018

Character

OR 95% CI

P-value

P for interaction

Age

  

0.795

 Below 60

1.253 (1.062, 1.479)

0.008

 

 Over 60

1.355 (1.196, 1.535)

<0.0001

 

PIR

  

0.318

 Below 1.3

1.200 (1.012, 1.422)

0.036

 

 1.3–3.5

1.402 (1.191, 1.651)

<0.0001

 

 Over 3.5

1.173 (0.929, 1.482)

0.178

 

BMI

  

0.25

 Below 25

1.392 (1.118, 1.732)

0.003

 

 25–30

1.324 (1.059, 1.655)

0.014

 

 Over 30

1.172 (1.011, 1.358)

0.035

 

Gender

  

0.051

 Male

1.428 (1.203, 1.695)

<0.0001

 

 Female

1.173 (1.011, 1.361)

0.035

 

Hypertension

  

0.645

 No

1.177 (0.972, 1.425)

0.095

 

 Yes

1.272 (1.121, 1.443)

<0.001

 

Diabetes

  

0.08

 No

1.320 (1.144, 1.524)

<0.001

 

 Pre-diabetes

1.513 (1.092, 2.096)

0.013

 

 Diabetes

1.091 (0.905, 1.314)

0.359

 

Hyperlipidemia

  

0.111

 No

1.583 (1.221, 2.053)

<0.001

 

 Yes

1.230 (1.092, 1.385)

<0.001

 

Work activity

  

0.497

 No

1.361 (1.162, 1.593)

<0.001

 

 Yes

1.263 (1.082, 1.475)

0.003

 

Alcohol use

  

0.405

 Never

1.581 (1.229, 2.035)

<0.001

 

 Former

1.266 (1.072, 1.496)

0.006

 

 Mild

1.250 (1.007, 1.552)

0.044

 

 Moderate

1.140 (0.851, 1.528)

0.377

 

 Heavy

1.409 (1.016, 1.954)

0.040

 

Smoke

  

0.643

 Never

1.342 (1.118, 1.611)

0.002

 

 Former

1.408 (1.150, 1.724)

0.001

 

 Now

1.171 (0.964, 1.422)

0.112