Fig. 4

Venn diagram showing the overlap of the subtypes of PA (A). OPLS-DA score plot showing the separation of patients belonging to each PA subtype group; Airway abnormalities (including patients with coexisting nodules and/or ILA), Pulmonary nodules only (excluding patients with coexisting airway abnormalities) and No PA in the RA patients (n=30) (B). Closely clustered patients indicate similarities in neutrophil activation status (CD11b and CD62L expression), neutrophil subtypes (% LDG and CD177 expression), calprotectin, as well as disease activity measures and demographic data