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Table 2 Predictors of survival in the uni- and multivariable analysis

From: Hypochromic red cells as a prognostic indicator of survival among patients with systemic sclerosis screened for pulmonary hypertension

Variables

Univariable analysis

Multivariable Cox regression analysis

p-value

n

p-value

n

Hypochromic erythrocytes

0.043

170

  

White blood cell count

0.298

170

  

Ferritin

0.353

160

  

Iron

0.702

160

  

Hemoglobin

0.290

170

  

MCH

0.301

170

  

MCV

0.143

170

  

Categoriala

 MCV ≤ 80 fl

0.920

163

  

 Hypochromic erythrocytes > 2%

0.018

163

0.031

145

Known prognostic predictors

 Sex

0.322

163

  

 Type of SSc

0.679

163

  

 DLCO ≤ 65% predicted

< 0.001

149

0.013

145

 ILD presence

0.066

163

  

 Age ≥ 60 years, baseline

0.040

160

  

 PVR ≥ 2 WU

0.041

161

  
  1. MCV mean corpuscular volume, SSc systemic sclerosis, DLCO diffusion capacity of the lung for carbon monoxide, ILD interstitial lung disease, PVR pulmonary vascular resistance
  2. aUnivariable categorical analyses were performed with Kaplan-Meier analysis, and all other analyses were Cox regression analyses