Fig. 2

FMT-Lpr mice have altered intestinal permeabilities and immunological states. Representative images of HE staining of the small intestine (A) and the large intestine (B). Scale bar, 50 μm. magnification × 400. ZO-1 expressions detected by immunofluorescence and the mRNA levels measured by RT-PCR in the small intestine (C) and the large intestine (D). Tnf, Il18, and Ifng mRNA expression levels in the small intestine (E) and Il6, Tnf, Il18, and Ifng mRNA expression levels in the large intestine (F). Flow cytometric analysis of the percentages of CD11b + cells gated on the CD45 + CD3 − CD19 − cells in the small intestine (G) and the percentages of B220 − IgD − CD138 + cell characterized as the plasma cells gated on the CD45 + cells in the large intestine (H). *p < 0.05. **p < 0.001. FMT-Lpr, n = 8 ~ 11; FMT-Mpj, n = 5 ~ 10; FMT-PBS, n = 5 ~ 7