Fig. 5

Differential enriched functional KEGG pathway in the pristane-induced lupus mice with different FMT. The characteristic KEGG functional pathways for each group based on the metagenome results were analyzed in the pairwise comparison, shown by LDA score > 2.0 between the FMT-Lpr and FMT-Mpj (A), the FMT-Lpr and FMT-PBS (B), and the FMT-Mpj and FMT-PBS (C). The KEGG functional pathway enriched by the differential metabolites analyzed in pairs between the FMT-Lpr and FMT-Mpj (D), the FMT-Lpr and FMT-PBS (E), the FMT-Mpj and FMT-PBS (F). G The relative abundances of the overlapped KEGG pathways including the cyanoamino acid metabolism (upper), valine, leucine, and isoleucine degradation (down) among the three groups. H The relative abundances of the L-isoleucine, L-valine, L-glutamate, L-tyrosine, and L-threonine among the three groups. *p < 0.05. **p < 0.001. FMT-Lpr, n = 11; FMT-Mpj, n = 10; FMT-PBS, n = 7