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Table 1 Baseline characteristics at first radiograph

From: Site-specific assessment of spinal radiographic progression improves detection of TNF blocker-associated disease modification in axial spondyloarthritis: longitudinal observational data from the Swiss Clinical Quality Management Registry

Parameter

All patients

Patients with complete covariate data

N

 

N

 

Male sex, N (%)

433

285 (65.8)

297

197 (66.3)

HLA-B27 positive, N (%)

392

316 (80.6)

297

240 (80.8)

Age, years

433

40.3 (11.0)

297

39.5 (10.6)

Symptom duration, years

425

13.8 (9.8)

297

13.5 (9.4)

BASDAI

369

4.2 (2.3)

286

4.3 (2.3)

ASDAS-CRP

351

2.8 (1.1)

276

2.9 (1.1)

CRP (mg/l), median (IQR)

365

8.0 (3.0; 11.0)

278

8.0 (4.0; 12.0)

Elevated CRP, N (%)

364

147 (40.4)

277

116 (41.9)

BASFI

373

3.1 (2.6)

288

3.1 (2.5)

BASMI

375

2.2 (2.0)

285

2.2 (2.5)

mSASSS median (IQR)

433

1.0 (0.0; 6.0)

297

1.0 (0.0; 6.0)

Mean (SD)

 

6.6 (12.5)

 

6.6 (12.6)

Syndesmophytes present, N (%)

433

148 (34.2)

297

98 (33.0)

EQ-5D

370

65.1 (21.6)

284

64.5 (21.5)

Current peripheral arthritis, N (%)

378

108 (28.6)

289

82 (28.4)

Current enthesitis, N (%)

381

207 (54.3)

288

171 (59.4)

BMI 25–30, N (%)

373

110 (29.5)

287

84 (29.3)

BMI > 30, N (%)

373

58 (15.6)

287

42 (14.6)

On NSAID treatment, N (%)

341

286 (83.9)

277

236 (85.2)

On TNFi treatment, N (%)

433

163 (37.6)

297

96 (32.3)

Ever TNFi treatment, N (%)

433

186 (43.0)

297

116 (39.1)

Years of TNFi treatment in treated patients

163

2.1 (1.7)

96

2.0 (1.6)

Current smokers, N (%)

366

140 (38.2)

285

104 (36.5)

Number exercise sessions per week

366

2.0 (0.0; 4.0)

286

2.0 (0.0; 4.0)

Patients with different number of radiographic intervals, N (%)

433

100

297

100

1 interval

294

67.9

182

61.3

2 intervals

92

21.2

76

25.6

3 intervals

35

8.1

28

9.4

4 intervals

11

2.5

10

3.4

5 intervals

1

0.2

1

0.3

  1. Except where indicated otherwise, values are the mean (SD). ASDAS-CRP Ankylosing Spondylitis Disease Activity Score using C-reactive protein levels, BASDAI Bath Ankylosing Spondylitis Disease Activity Index, BASFI Bath Ankylosing Spondylitis Functional Index, BASMI Bath Ankylosing Spondylitis Metrology Index, BMI Body mass index, CRP C-reactive protein (CRP) levels, EQ-5D EuroQol 5-domains, HLA-B27 Human leucocyte antigen B27, mSASSS modified Stoke Ankylosing Spondylitis Spinal Score, NSAID Nonsteroidal anti-inflammatory drug, TNFi Tumour necrosis factor inhibitor