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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: TAK-715 alleviated IL-1β-induced apoptosis and ECM degradation in nucleus pulposus cells and attenuated intervertebral disc degeneration ex vivo and in vivo

Fig. 1

TAK-715 effects on NPC viability. A Chemical structure of TAK-715. B A CCK8 assay was used to determine the cytotoxic effects of TAK-715 on NP cells for 24 h and 48 h. C Western blot analysis was used to analyze p38 and p-p38 protein expression in NPCs treated with various concentrations of TAK-715; D the immunoblot ratio of p-p38/p38 was quantitatively analyzed. The data are presented as the mean ± SD (*P < 0.05; **P < 0.01; ***P < 0.001)

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