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Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: TAK-715 alleviated IL-1β-induced apoptosis and ECM degradation in nucleus pulposus cells and attenuated intervertebral disc degeneration ex vivo and in vivo

Fig. 7

TAK-715 ameliorates the progression of intervertebral disc degeneration in a rat puncture model. A MRI images of rat intervertebral discs (n = 6). B Pfirrmann score of caudal MRI images of rats after surgery and injection with TAK-715; C HE and SO/FG staining of rat intervertebral discs (upper scale bar:200 μm, lower scale bar:20 μm). D The histological grades were evaluated (n = 6). The data are presented as the mean ± SD (*P < 0.05; **P < 0.01; ***P < 0.001)

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Arthritis Research & Therapy

ISSN: 1478-6362

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