Fig. 8From: TAK-715 alleviated IL-1β-induced apoptosis and ECM degradation in nucleus pulposus cells and attenuated intervertebral disc degeneration ex vivo and in vivoSchematic illustration of TAK-715 treatment in NPCs. TAK-715 reduced inflammation, apoptosis, and degradation of the ECM in NPCs by inhibiting the p38MAPK pathwayBack to article page