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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Notch signaling is activated in knee-innervating dorsal root ganglia in experimental models of osteoarthritis joint pain

Fig. 5

Notch signaling pathway genes are upregulated in knee-innervating DRG after DMM surgery. Quantitative RT-PCR analysis of Jag1 (A), Adam17 (B), Rbpj (C), and Hes1 (D) mRNA expression in ipsilateral L3-L5 DRGs harvested from mice 12 and 26 weeks after DMM or sham surgery (N = 6 mice per group for 12 weeks, and N = 3 mice per group for 26 weeks after surgeries). Gene expression is presented as 2−ΔCT(Gene of interest – Gapdh). Each dot represents one mouse

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