Activated CD90/Thy-1 fibroblasts co-express the Δ133p53β isoform and are associated with highly inflamed rheumatoid arthritis

Table 1 Clinical and demographic characteristics of the rheumatoid arthritis and osteoarthritis cohorts

	Rheumatoid arthritis	Osteoarthritis
Patients (no.)	37^a	20
Synovia	40	20
Female, n (%)	30 (82)	14 (70)
Age, years (mean ± SE)	62 ± 2	71 ± 2
Disease duration, years	17 ± 2	12 ± 3
RF positive (%)^b	90	n.d
CCP⁺ (%)^b	84	n.d
CRP⁺ (mg/dL)	10 ± 2	n.d
Radiographic erosions^d	88	n.d
Subcutaneous nodules^d	56	n.d
Disease-modifying anti-rheumatic drugs [no. (%)]
Prednisone	9 (36)	–
bDMARDs	3 (12)	–
cDMARDs	10 (40)	–

For several variables, there was missing data in ≥ 1 of the patients
bDMARD, biological DMARD; cDMARD, conventional DMARD
^aThirty-seven people with RA provided 40 synovia including 3 individuals providing 2 separate synovia at different times from 13 to 16 months apart
^bPercentage values for rheumatoid factor (RF) or anti-citrullinated peptide (CCP)⁺ are from 21/37 patients (57%) and 19/37 (51%) providing synovia
^cOf patients providing synovia, data for erosions are from 24/37 patients (65%), and data for nodules are from 25/37 patients (68%)
^dDisease-modifying anti-rheumatic drugs (DMARD) reconciled at the time of tissue collection were available from 25/37 of patients (68%)

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