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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Glutathione peroxidase 3 is a novel clinical diagnostic biomarker and potential therapeutic target for neutrophils in rheumatoid arthritis

Fig. 5

Transcriptomic analysis of neutrophils in autoimmune disease patients compared with HC (control). A Venn diagram displaying the overlap of the five gene expression datasets, including RA (GSE116899 and GSE15474), SLE (GSE153781), SJIA (GSE122552), and AOSD (GSE150996). B, C Box plots of expression data before and after normalization. D PCA plot analysis of normalized data. E The expression levels of NADPH oxidase-related genes in normalized data. F The mRNA expression level of CYBB was detected by qPCR. FCM analysis of ROS MFI in neutrophils with HC, SLE, and RA: G MFI was calculated using FlowJo software. H Statistical analysis was performed in Prism

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Arthritis Research & Therapy

ISSN: 1478-6362

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