Bivariable | Multivariable | ||||||
---|---|---|---|---|---|---|---|
Variable | OR | 95% CI | P-value | OR | 95% CI | P-value | |
Female sex | 0.59 | (0.35–1.02) | 0.060 | 0.52 | (0.28–0.97) | 0.039 | |
TNF-i | 1.76 | (0.83–3.75) | 0.143 | 0.99 | (0.41–2.37) | 0.977 | |
Disease (ref RA) | AS | 1.35 | (0.66–2.74) | 0.407 | 1.11 | (0.45–2.73) | 0.820 |
PsA | 1.94 | (1.04–3.60) | 0.036 | 1.51 | (0.74–3.07) | 0.256 | |
Smoking (ref smoker) | Non-smoker | 3.77 | (1.35–10.51) | 0.011 | 4.34 | (1.53–12.28) | 0.006 |
Ex-smoker | 0.53 | (0.06–4.74) | 0.596 | 0.64 | (0.07–5.83) | 0.691 | |
Second-line treatment | 1.06 | (0.61–1.84) | 0.831 | 1.65 | (0.91–3.00) | 0.100 | |
Corticosteroids | 0.70 | (0.37–1.33) | 0.273 | - | - | - | |
Concomitant treatment | 0.87 | (0.50–1.50) | 0.619 | 0.89 | (0.48–1.63) | 0.707 | |
Moderate-high activitya | 0.38 | (0.12–1.25) | 0.113 | - | - | - | |
Age at diagnosis | 1.00 | (0.98–1.02) | 0.663 | - | - | - | |
Age at onset | 0.99 | (0.97–1.01) | 0.425 | 1.01 | (0.98–1.03) | 0.530 | |
Disease duration | 0.96 | (0.92–1.00) | 0.052 | 0.94 | (0.89–0.98) | 0.010 | |
Charlson Comorbidity Index | 0.96 | (0.79–1.17) | 0.677 | - | - | - | |
Time in treatment | 1.01 | (1.01–1.02) | 0.001 | 1.01 | (1.01–1.02) | < 0.001 | |
Year of discontinuation of treatment | 1.00 | (0.94–1.06) | 0.991 | 0.99 | (0.92–1.06) | 0.712 |