A higher intramuscular fat in vastus medialis is associated with functional disabilities and symptoms in early stage of knee osteoarthritis: a case–control study

Table 2 Muscle volume and intraMAT differences between the early knee OA and healthy control groups

	Adjusted mean (SE)		p-value	Adjusted mean difference [95% CI]
	Healthy control	Early knee OA	p-value	Early knee OA against control
Muscle volume, cm³
Quadriceps femoris	1089.6 ± 25.4	1139.2 ± 32.5	0.235	49.6 [− 33.5, 132.7]
Rectus femoris	149.1 ± 4.5	162.1 ± 5.7	0.080	13.1 [− 1.6, 27.7]
Vastus intermedius	319.2 ± 8.2	315.4 ± 10.4	0.777	− 3.8 [− 30.5, 23.0]
Vastus lateralis	347.3 ± 10.1	379.2 ± 12.9	0.058	31.8 [− 1.2, 64.8]
Vastus medialis	274.0 ± 7.0	282.5 ± 9.0	0.460	8.5 [− 14.5, 31.6]
IntraMAT, %
Quadriceps femoris	6.7 ± 0.3	7.7 ± 0.4	0.035	1.0 [0.1, 1.9]
Rectus femoris	5.5 ± 0.2	6.1 ± 0.3	0.138	0.6 [− 0.2, 1.3]
Vastus intermedius	7.4 ± 0.3	7.9 ± 0.4	0.287	0.5 [− 0.5, 1.6]
Vastus lateralis	7.9 ± 0.4	8.6 ± 0.5	0.253	0.7 [− 0.5, 1.8]
Vastus medialis	6.0 ± 0.3	8.2 ± 0.4	< 0.001	2.2 [1.2, 3.3]

OA Osteoarthritis, SE Standard error, 95% CI 95% confidence interval, IntraMAT Intramuscular fat
The adjusted mean differences were calculated with adjustments for age, sex, and BMI and presented as the early knee OA group values against the healthy control group

ISSN: 1478-6362