Fig. 3From: Expression of S100A8 protein on B cells is associated with disease activity in patients with systemic lupus erythematosusA Association of expression levels of S100A8 and S100A8/A9 on B cells with disease activity. The MFI of S100A8 on the B cell surface correlated with SLEDAI. We used monoclonal antibody 27E10 which recognizes S100A8/A9 dimers and monoclonal antibody 3H2617 which recognizes S100A8. B S100A8 on the surface of peripheral blood B cells was evaluated using flow cytometry in patients with SLE (N = 4) whose blood samples were obtained before and after treatment (initial or strengthened therapy). In all four patients, S100A8 expression was significantly reduced after treatment. C The change of anti-S100A8 staining patterns before and after the treatment in one patient with SLE (SLE-2)Back to article page