Weight standardized | Max complex IV standardized | CS activity standardized | ||||
---|---|---|---|---|---|---|
Variablea | Mean difference (95% CI) | p-value | Mean difference (95% CI) | p-value | Mean difference (95% CI) | p-value |
Leak rate with fatty acid substrate (PC) | − 3.19 (− 4.50, − 1.89) | < 0.01 | 0.01 (− 0.004, 0.02) | 0.17 | − 0.06 (− 0.26, 0.14) | 0.59 |
OXPHOS capacity | − 6.69 (− 22.18, 8.80) | 0.41 | 0.14 (0.02, 0.26) | 0.03 | 0.82 (− 0.91, 2.55) | 0.36 |
Maximal rate of uncoupler-stimulated respiration | − 17.27 (− 32.28, − 2.25) | 0.03 | 0.09 (− 0.04, 0.22) | 0.17 | − 0.18 (− 1.76, 1.39) | 0.82 |
Max complex IV activity (mitochondrial content)b | − 74.45 (− 108.90, − 40.01) | < 0.01 | − 3.01 (− 6.79, 0.77) | 0.13 |