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  1. A new alkaline phosphotungstate reduction reaction is introduced in a simple procedure for the determination of the total urate-equivalent chromogens (TUEC) for the first time in serum, aiming that these subst...

    Authors: Ahmed Nabil Hegazi Ph.D.

    Citation: Arthritis Research & Therapy 2001 3:E004

    Content type: Non-peer-reviewed research

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  2. A Modification of the method previously introduced by Fossati et al [1] is accomplished for the estimates of protein bound urate, for the first time, as well as the loosely associated urate in serum.

    Authors: Ahmed Nabil Hegazi Ph.D.

    Citation: Arthritis Research & Therapy 2001 3:E003

    Content type: Non-peer-reviewed research

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  3. In this paper, it has been experimentally proved for the first time that urate is present in human serum bound to proteins. The protein-bound urates, when liberated, absorb in the ultraviolet light at waveleng...

    Authors: Ahmed Nabil Hegazi Ph.D.

    Citation: Arthritis Research & Therapy 2001 3:E002

    Content type: Non-peer-reviewed research

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  4. Interleukin-11 (IL-11) is a pleiotropic cytokine that regulates the growth and development of hematopoietic stem cells and decreases the proinflammatory mediators of cytokine and nitric oxide production. In an...

    Authors: Larry Moreland, Ron Gugliotti, Kevin King, Walter Chase, Michael Weisman, Thomas Greco, Rose Fife, Joseph Korn, Robert Simms, John Tesser, Jan Hillson, Jacques Caldwell, Thomas Schnitzer, David Lyons and Ullrich Schwertschlag

    Citation: Arthritis Research & Therapy 2001 3:247

    Content type: Research article

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  5. Deficiency in the classical pathway complement components displays a hierarchical association with the development of systemic lupus erythematosus (SLE). In addition, SLE causes consumption of complement. C1q-...

    Authors: Marina Botto

    Citation: Arthritis Research & Therapy 2001 3:207

    Content type: Commentary

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  6. B cells and B-cell/T-cell collaborations are instrumental in the pathophysiology of systemic lupus erythematosus (SLE). This commentary highlights in particular the newly discovered role of B-cell-activating f...

    Authors: Thomas Dörner and Chaim Putterman

    Citation: Arthritis Research & Therapy 2001 3:197

    Content type: Commentary

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  7. The synovial membrane (SM) of affected joints in ankylosing spondylitis (AS) is infiltrated by germinal center-like aggregates (foci) of lymphocytes similar to rheumatoid arthritis (RA). We characterized the r...

    Authors: Jan Voswinkel, Kerstin Weisgerber, Michael Pfreundschuh and Angela Gause

    Citation: Arthritis Research & Therapy 2001 3:189

    Content type: Research article

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  8. Hypothalamic–pituitary–adrenal underactivity has been reported in rheumatoid arthritis (RA). This phenomenon has implications with regard to the pathogenesis and treatment of the disease. The present study was...

    Authors: Patrick H Dessein, Barry I Joffe, Anne E Stanwix and Zubair Moomal

    Citation: Arthritis Research & Therapy 2001 3:183

    Content type: Research article

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  9. In 44 consecutive patients with systemic sclerosis (SSc), plasma concentrations of von Willebrand factor (vWf) were higher than those of the vWf propeptide, but the propeptide showed less variability within pa...

    Authors: Agneta Scheja, Anita Åkesson, Pierre Geborek, Marie Wildt, Claes B Wollheim, Frank A Wollheim and Ulrich M Vischer

    Citation: Arthritis Research & Therapy 2001 3:178

    Content type: Research article

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  10. Recombinant adenoviruses are straightforward to produce at high titres, have a promiscuous host-range, and, because of their ability to infect nondividing cells, lend themselves to in vivo gene delivery. Such adv...

    Authors: Christopher H Evans, Steven C Ghivizzani, Thomas A Oligino and Paul D Robbins

    Citation: Arthritis Research & Therapy 2001 3:142

    Content type: Commentary

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  11. The classification of T helper cells into type 1 (Th1) and type 2 (Th2) led to the hypothesis that Th1 cells and their cytokines (interleukin [IL]-2, interferon [IFN]-γ) are involved in cell-mediated autoimmun...

    Authors: Argyrios N Theofilopoulos, Stefanos Koundouris, Dwight H Kono and Brian R Lawson

    Citation: Arthritis Research & Therapy 2001 3:136

    Content type: Commentary

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  12. Inflammatory responses provoked by pathogens are antigen-specific in their induction but are nonspecific in their effects. Consequently, they are potentially damaging to the host that produces them. In additio...

    Authors: Don Mason

    Citation: Arthritis Research & Therapy 2001 3:133

    Content type: Commentary

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  13. Citation: Arthritis Research & Therapy 2001 3(Suppl 2):P002

    Content type: Meeting abstract

    Published on:

    This article is part of a Supplement: Volume 3 Supplement 2

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