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Page 125 of 127

  1. Content type: Research article

    Acute-phase serum amyloid A (A-SAA) is a major component of the acute-phase response. A sustained acute-phase response in rheumatoid arthritis (RA) is associated with increased joint damage. A-SAA mRNA express...

    Authors: Rosemary O'Hara, Evelyn P Murphy, Alexander S Whitehead, Oliver FitzGerald and Barry Bresnihan

    Citation: Arthritis Research & Therapy 2000 2:142

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  2. Content type: Review

    Normally the immune response is restricted to the peripheral secondary lymphoid organs. However, additional ectopic lymphoid tissue may develop at chronic sites of inflammation. In the synovium of rheumatoid a...

    Authors: Hye-Jung Kim and Claudia Berek

    Citation: Arthritis Research & Therapy 2000 2:126

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  3. Content type: Commentary

    Osteoarthritis is complex in genetics, pathogenesis, monitoring and treatment. Current treatment of osteoarthritis does not influence progression. Much could be gained by more effective 'low-tech-low-cost' tre...

    Authors: L Stefan Lohmander

    Citation: Arthritis Research & Therapy 2000 2:95

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  4. Content type: Research article

    Serum and synovial tissue expression of the matrix metalloproteinase (MMP)-2 and -9 and their molecular regulators, MMP-14 and TIMP-2 was examined in 28 patients with inflammatory early synovitis and 4 healthy...

    Authors: Raphaela Goldbach-Mansky, Jennifer M Lee, Joseph M Hoxworth, David Smith II, Paul Duray, H Ralph Schumacher Jr, Cheryl H Yarboro, John Klippel, David Kleiner and Hani S El-Gabalawy

    Citation: Arthritis Research & Therapy 2000 2:145

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  5. Content type: Review

    Autoantibodies present in the serum of patients with a variety of inflammatory diseases have proven useful as diagnostic markers and as probes with which to elucidate biochemical and signaling pathways. The me...

    Authors: Paul J Utz,, Timothy J Gensler and Paul Anderson

    Citation: Arthritis Research & Therapy 2000 2:101

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  6. Content type: Commentary

    A chance observation has led to the development of a new murine model for inflammatory arthritis. Arthritis is induced, and transferred, by T-cell-dependent antibodies to glucose-6-phosphate isomerase. This en...

    Authors: Hugh McDevitt

    Citation: Arthritis Research & Therapy 2000 2:85

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  7. Content type: Research article

    CD8+ T cells dominate the lymphocyte population insynovial fluid in chronic inflammatory arthritis. It is known that theseCD8+ T cells are often clonally or oligoclonally expanded, but theirspecificity and their ...

    Authors: Linda C Tan, Alastair G Mowat, Chrysoula Fazou, Tim Rostron, Helen Roskell, P Rod Dunbar, Claire Tournay, François Romagné, Marie-Alix Peyrat, Elisabeth Houssaint, Marc Bonneville, Alan B Rickinson, Andrew J McMichael and Margaret FC Callan

    Citation: Arthritis Research & Therapy 2000 2:154

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  8. Content type: Review

    Cytokines play a critical role in the normal development and function of the immune system. On the other hand, many rheumatologic diseases are characterized by poorly controlled responses to or dysregulated pr...

    Authors: Robert A Ortmann, Tammy Cheng, Roberta Visconti, David M Frucht and John J O'Shea

    Citation: Arthritis Research & Therapy 1999 2:16

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  9. Content type: Research article

    IFN-γ was measured in supernatants after in vitro stimulation of peripheral blood mononuclear cells with collagen type II (CII), purified protein derivative or influenza virus. IFN-γ production in response to CII...

    Authors: Louise Berg, Johan Rönnelid, Carani B Sanjeevi, Jon Lampa and Lars Klareskog

    Citation: Arthritis Research & Therapy 1999 2(Suppl 1):75

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    This article is part of a Supplement: Volume 2 Supplement 1

  10. Content type: Research article

    In the present study, we searched for mutant PTEN transcripts in aggressive rheumatoid arthritis synovial fibroblasts (RA-SF) and studied the expression of PTEN in RA. By automated sequencing, no evidence for the...

    Authors: Thomas Pap, Juliane K Franz, Klaus M Hummel, Elvira Jeisy, Renate Gay and Steffen Gay

    Citation: Arthritis Research & Therapy 1999 2:59

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  11. Content type: Research article

    The present study was designed to analyze the level of B-cell clonal diversity in patients with rheumatoid arthritis by using HCDR3 (third complementarity determining region of the rearranged heavy chain varia...

    Authors: Kenji Itoh, Varsha Patki, Richard A Furie, Elliot K Chartash, Rita I Jain, Lewis Lane, Stanley E Asnis and Nicholas Chiorazzi

    Citation: Arthritis Research & Therapy 1999 2(Suppl 1):50

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    This article is part of a Supplement: Volume 2 Supplement 1

  12. Content type: Review

    Case reports suggest that solvents are associated with various connective tissue diseases (systemic sclerosis, scleroderma, undifferentiated connective tissue disease, systemic lupus erythematosis, and rheumat...

    Authors: David H Garabrant and Constantine Dumas

    Citation: Arthritis Research & Therapy 1999 2:5

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