Arthritis Research & Therapy

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Commentary

The “myth” of loss of angiogenesis in systemic sclerosis: a pivotal early pathogenetic process or just a late unavoidable event?

Marco Matucci-Cerinic, Mirko Manetti, Cosimo Bruni, Ines Chora, Silvia Bellando-Randone, Gemma Lepri, Amato De Paulis and Serena Guiducci

Published on: 6 July 2017
Research article

Coculture of bovine cartilage with synovium and fibrous joint capsule increases aggrecanase and matrix metalloproteinase activity

Per Swärd, Yang Wang, Maria Hansson, L. Stefan Lohmander, Alan J. Grodzinsky and André Struglics

Published on: 5 July 2017
Research article

Factors associated with initial or subsequent choice of biologic disease-modifying antirheumatic drugs for treatment of rheumatoid arthritis

Yinzhu Jin, Rishi J. Desai, Jun Liu, Nam-Kyong Choi and Seoyoung C. Kim

Published on: 5 July 2017
Research article

Abatacept reduces synovial regulatory T-cell expression in patients with psoriatic arthritis

Agnes Szentpetery, Eric Heffernan, Martina Gogarty, Lisa Mellerick, Janet McCormack, Muhammad Haroon, Musaab Elmamoun, Phil Gallagher, Genevieve Kelly, Aurelie Fabre, Brian Kirby and Oliver FitzGerald

Published on: 5 July 2017
Research article

Interaction of the GCKR and A1CF loci with alcohol consumption to influence the risk of gout

Humaira Rasheed, Lisa K. Stamp, Nicola Dalbeth and Tony R. Merriman

Published on: 5 July 2017

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Review

Use of NSAIDs in treating patients with arthritis

Leslie J Crofford

Published on: 24 July 2013
Research article

Remission in psoriatic arthritis: is it possible and how can it be predicted?

Tajvur P Saber, CT Ng, Guillaume Renard, Bernadette M Lynch, Eliza Pontifex, Ceara AE Walsh, Alexia Grier, Marian Molloy, Barry Bresnihan, Oliver FitzGerald, Ursula Fearon and Douglas J Veale

Published on: 18 May 2010
Research article

Collagen-induced arthritis in common marmosets: a new nonhuman primate model for chronic arthritis

Michel PM Vierboom, Elia Breedveld, Ivanela Kondova and Bert A 't Hart

Published on: 26 October 2010
Review

Complement and systemic lupus erythematosus

Mark J Walport

Published on: 9 May 2002
Review

Microbes, the gut and ankylosing spondylitis

Mary-Ellen Costello, Dirk Elewaut, Tony J Kenna and Matthew A Brown

Published on: 6 June 2013

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Article collections

Rheumatology around the world

Measuring meaningful change in lupus clinical trials

Biology and clinical applications of stem cells for autoimmune and musculoskeletal disorders

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Editors-in-Chief

Professor Christopher Buckley, University of Birmingham and University of Oxford, UK
Professor Harris Perlman, Northwestern University, USA

Aims and scope

Arthritis Research & Therapy is an international, peer-reviewed online journal, publishing original research, reviews, commentaries and reports. The major focus of the journal is on cellular and molecular mechanisms of arthritis, musculoskeletal conditions and systemic autoimmune rheumatic diseases and translation of this knowledge into advances in clinical care. Original basic, translational laboratory and clinical research is considered for publication along with results of early and late phase therapeutic trials.

Review series: New technologies

Written by renowned experts in the field, this collection of open access Review articles explores the use of RNA sequencing, cytometry, metabolomics and next-generation DNA sequencing in rheumatic disease.

Reflections of a rheumatologist

The role of mitochondria in immune-mediated disease: the dangers of a split personality

Read more from David Pisetsky

Featured review: Fibroblast-like synoviocyte metabolism in the pathogenesis of rheumatoid arthritis

New Content Item In this review, Bustamante and colleagues show how fibroblast-like synoviocytes in RA patients differ from healthy synovial fibroblasts, not only in their marker expression, proto-oncogene expression, or their epigenetic changes, but also in their intracellular metabolism.

"Whether this truly constitutes an option to increase the drug armamentarium in rheumatic diseases beyond biological and kinase inhibitor therapies remains to be determined."