From: Safety of rituximab in the treatment of B cell malignancies: implications for rheumatoid arthritis
 | First infusion | Second infusion | ||
---|---|---|---|---|
Adverse event | Placebo | Rituximab (1000 mg) | Placebo | Rituximab (1000 mg) |
Any adverse event | 30 | 36 | 15 | 17 |
Transient hypotension | 20 | 13 | 10 | 12 |
Transient hypertension | 10 | 9 | 5 | 3 |
Flushing | - | 4 | - | 1 |
Pruritus | - | 6 | - | - |
Rash | - | 4 | - | - |
Dyspnoea | - | 3 | - | - |
Pharynx discomfort | - | 3 | - | - |
Pyrexia | - | 3 | - | - |
Headache | - | 2 | - | - |