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Figure 4 | Arthritis Res Ther

Figure 4

From: Induction of IL-10-producing CD4+CD25+T cells in animal model of collagen-induced arthritis by oral administration of type II collagen

Figure 4

Comparisons of (a) IL-10 and (b) transforming growth factor (TGF)-β production by mononuclear lymphocytes from lymphoid organs of tolerized and nontolerized mice. Organs were extracted from normal DBA/1, and tolerized and nontolerized collagen-induced arthritis (CIA) mice at 5 weeks after primary immunization with type II collagen (CII) for induction of CIA. Mononuclear cells were isolated from the Peyer's patch and the spleen, and production of IL-10 and TGF-β was assessed by sandwich ELISA analyses of culture supernatants. The data represent average values from three independent measurements.

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Arthritis Research & Therapy

ISSN: 1478-6362

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