| No. of micea | Incidence (%)b | Mean scorec at day 64 | Mean day of onsetd |
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DBA/1J-lpr/lpr | 34 | 44* e | 1.6 ± 0.75*f | 51 ± 14 |
DBA/1J-lpr/+ | 33 | 81 | 5 ± 1.1 | 41 ± 6 |
- DBA/1J-lpr/lpr and DBA/1J-lpr/+ mice were scored for arthritic lesions as described in Materials and methods. A summary of disease course in DBA/1J-lpr/lpr and their control littermates DBA/1J-lpr/+ is shown. a18 of the lpr/lpr mice and 16 of the lpr/+ mice are from Ma and co-workers [45]. bNumber of diseased mice divided by all mice. cScore of diseased mice divided by all mice ± SEM. dTotal of days of onset divided by the number of diseased mice ± SD. * eP < 0.05, χ2 test. * fP < 0.05, Mann–Whitney U test.