Table 2 Interferon-γ production by cytotoxic T lymphocyte lines after incubation on anti-hamster IgG or anti-CD3 in the presence or absence of Lip-OspA, Met-Asp-Pro-OspA, recombinant interleukin-2 or lipopolysaccharide

Anti-haIgG

0.2

0.3

   + Lip-OspA

2.3^a (11.5)

0.2 (<1)

   + MDP-OspA

0.3 (1.5)

0.2 (<1)

   + rec. IL-2

0.5 (2.5)

0.4 (1.3)

   + LPS

0.2 (1.0)

0.4 (1.3)

0.03 ng per well anti-CD3

0.2

0.3

   + anti-CD3 + Lip-OspA

5.4^a (27)

0.2 (<1)

   + anti-CD3 + MDP-OspA

0.2 (1.0)

0.3 (1.0)

   + anti-CD3 + rec. IL-2

0.8^a (4.0)

0.6 (2.0)

   + anti-CD3 + LPS

0.3 (1.5)

0.1 (<1)

0.3 ng per well anti-CD3

4.9

7.2

   + anti-CD3 + Lip-OspA

29.1^a (5.9)

6.8 (<1)

   + anti-CD3 + MDP-OspA

6.0 (1.2)

9.5 (1.3)

   + anti-CD3 + rec. IL-2

10.9^a (2.2)

10.2 (1.4)

   + anti-CD3 + LPS

2.7 (<1)

7.2 (1.0)