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Figure 1 | Arthritis Res Ther

Figure 1

From: The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+T cells

Figure 1

Depletion of CD25-expressing cells by anti-CD25 treatment. Mice immunized with methylated bovine serum albumin (mBSA) were injected intraperitoneally with 0.5 mg PC61 (anti-CD25) or rat IgG as control 4 and 2 days before arthritis induction. Representative example for flow-cytometric assessment of depletion in spleen cells, using a non-cross-reactive anti-CD25 antibody (7D4) at the time of arthritis induction (day 0).

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Arthritis Research & Therapy

ISSN: 1478-6362

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