From: Catabolic stress induces expression of hypoxia-inducible factor (HIF)-1α in articular chondrocytes: involvement of HIF-1α in the pathogenesis of osteoarthritis
Mankin grade
Donor
Age (y)
Sex
Disease duration (y)
Intact region
Degenerated region
1
61
Female
5.5
3
7
2
62
6.0
4
9
64
Male
8.4
8
66
11.5
5
67
9.6
6
68
72
9.0