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Table 1 Genes that changed significantly in all the arthritic rat blood samples

From: Identification of blood biomarkers of rheumatoid arthritis by transcript profiling of peripheral blood mononuclear cells from the rat collagen-induced arthritis model

Probe set

Fold change (CIA/control)

Gene description

 

Day 10

Day 21

Day 28

 

1367612_at

4.94

4.31

2.10

Mgst1: microsomal glutathione S-transferase 1

1367816_at

1.89

2.58

1.51

GIIg15b: protein similar to 2300002F06Rik

1367900_at

4.93

4.56

2.93

Gyg: glycogenin (glycogenin glucosyltransferase)

1367904_at

--1.84

--1.76

--1.49

Resp18: regulated endocrine-specific protein 18

1369584_at

1.76

2.32

1.91

Socs3 (Cish3): suppressor of cytokine signaling 3

1369956_at

2.81

2.82

1.98

Ifngr: similar to interferon gamma receptor

1370119_at

3.10

2.73

1.86

Lst1: member of the LST-1 protein family

1370249_at

3.01

3.99

1.92

Bzrp: peripheral-type benzodiazepine receptor

1371916_at

2.64

3.29

1.60

Sepr: selenoprotein R

1372150_at

--2.24

--2.39

--1.72

Usp10: human ubiquitin specific protease 10 like

1372248_at

--1.88

--3.11

--1.76

SESN1: p53 regulated PA26 nuclear protein

1372691_at

4.46

6.19

2.32

Upp1: uridine phosphorylase 1

1373656_at

2.83

4.03

1.74

--

1374375_at

3.45

5.60

2.21

2610034M16Rik

1377092_at

3.61

2.38

3.71

 

1377110_at

--1.49

--2.60

--1.48

Plxdc1: plexin repeat containing family member

1386052_at

--1.80

--2.70

--1.58

 

1386879_at

3.35

5.20

2.36

Lgals3: Galectin-3

1386908_at

2.66

2.32

1.61

Glrx1: Glutaredoxin

1387568_at

3.68

4.65

1.82

Pirb: paired immunoglobulin-like receptor-B

1387599_a_at

2.73

4.12

1.76

Nqo1: NADH:NADPH diaphorase

1388054_a_at

3.64

3.31

1.98

Cspg2: chondroitin sulfate proteoglycan 2 (versican)

1388142_at

3.82

3.15

1.90

Cspg2: chondroitin sulfate proteoglycan 2 (versican)

1388265_x_at

1.75

2.60

2.28

Cspg2: chondroitin sulfate proteoglycan 2 (versican)

1388416_at

3.10

2.03

1.99

--

1388528_at

--1.50

--2.24

--1.43

Fbl: Fibrillarin

1389006_at

2.15

1.89

1.46

Mpeg1: member of the membrane attack complex

1389408_at

2.91

3.09

1.58

 
  1. Listed are probe sets for genes that showed significant difference between the arthritic and control rat blood identified by analysis of variance and filtered by empirical cutoffs. Probe set: identification of known genes and expressed sequence tags on the chip; Fold change: fold change values that was calculated between the arthritic samples and the time-matched controls; gene description: description of the genes encoded by the corresponding probe set.
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Arthritis Research & Therapy

ISSN: 1478-6362

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