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Table 2 Treatment terminations for ineffectiveness in original and re-employed methotrexate therapies

From: Methotrexate in rheumatoid arthritis is frequently effective, even if re-employed after a previous failure

  

Re-employed course

Total

  

No inefficacy

Inefficacy

 

Original course

No inefficacy

19 (9.7 ± 3.1/11.4 ± 4.9)

9 (10.0 ± 4.0/15.8 ± 6.5)

28 (9.8 ± 3.3/12.9 ± 5.8)

 

Inefficacy

23 (11.8 ± 4.5/16.8 ± 5.6)

28 (14.5 ± 5.3/18.8 ± 5.2)

51 (13.3 ± 5.1/17.9 ± 5.4)

Total

42 (10.9 ± 4.1/14.4 ± 5.9)

37 (13.5 ± 5.3/18.1 ± 5.6)

79 (12.1 ± 4.8/16.1 ± 6.0)

  1. The numbers in parentheses are the doses in the original methotrexate/re-employed methotrexate courses (mean ± standard deviation) in mg/week). The percentage of patients who were concordant for the presence or absence of inefficacy was 60.3% (P = 0.022, by McNemar test).
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Arthritis Research & Therapy

ISSN: 1478-6362

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